The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated.
Use with caution in dogs with a history of seizures.
How can I get the rebates?
Since we get our stock from third-party suppliers, it is not possible to get any rebates.
How effective is Credelio (lotilaner)?
In well-controlled European laboratory studies, Credelio began to kill fleas four hours after administration or infestation, with greater than 99% of fleas killed within eight hours after administration or infestation for 35 days. In a well-controlled U.S. laboratory study, Credelio demonstrated 100% effectiveness against adult fleas 12 hours after administration or infestation for 35 days.
In a 90-day well-controlled U.S. field study conducted in households with existing flea infestations of varying severity, the effectiveness of Credelio against fleas on Days 30, 60 and 90 compared to baseline was 99.5%,100%, and 100%, respectively. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating fleas.
In well-controlled laboratory studies, Credelio demonstrated > 97% effectiveness against Amblyomma americanum, Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus ticks 48 hours after administration or infestation for 30 days. In a well-controlled European laboratory study, Credelio started killing Ixodes ricinus ticks within four hours after administration.
Palatability: In the U.S. field study, which included 567 doses administered to 198 dogs, 80.4% of dogs voluntarily consumed Credelio when offered by hand or in an empty bowl, an additional 13.6% consumed Credelio when offered with food, and 6.0% required placement of the chewable tablet in the back of the dog’s mouth.
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